Evaluation of A Reverse Transcriptase (Rt) Loop Mediated Isothermal Amplification Assay for Detection of Hepatitis C Genotypes 1-4 Viruses Under Limited Logistical Conditions

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Evaluation of A Reverse Transcriptase (Rt) Loop Mediated Isothermal Amplification Assay For Detection Hepatitis C Genotypes 1-4 Viruses Under Limited Logistical Conditions

Hepatitis C Virus remains a major public health concern in many parts of the world due to its long sero-conversion period presenting it as a high risk in transfusion related transmission. The transfusion related transmission still remains a concern in many developing countries and resource related settings [1] which are highly dependent on serological tests for diagnosis and routine screening o...

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A reverse transcriptase-loop mediated isothermal amplification assay (RT-LAMP) for rapid detection of bovine viral diarrhea virus 1 and 2

Bovine viral diarrhea virus (BVDV) is a pathogen that infects cattle, and is globally important. It causes substantial financial losses to the livestock industry. In the current study, a one-step reverse transcriptase-loop-mediated isothermal amplification (RT-LAMP) assay was set up for rapid and efficient detection of BVDV. For this purpose, four primers were designed to recognize six distinct...

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Reverse transcription-loop-mediated isothermal amplification assay for rapid detection of hepatitis E virus.

The one-step single-tube betaine-free reverse transcription (RT)-loop-mediated isothermal amplification assay was developed for rapid diagnosis of hepatitis E virus. This assay amplified the target gene in less than 45 min (even as short as 20 min) under isothermal conditions at 63 degrees C, and the sensitivity of this assay was 100-fold greater than that of RT-PCR. This assay demonstrated a d...

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ژورنال

عنوان ژورنال: Journal of Human Virology & Retrovirology

سال: 2017

ISSN: 2373-6453

DOI: 10.15406/jhvrv.2017.05.00145